Inflammatory signs in the blood can predict depression in pregnancy: study | The health – After world

While the birth of a new life is every woman’s greatest joy, it also brings with it something not very pleasant – depression. A study has now shown that signs of inflammation in the blood can reliably predict and identify severe depression during pregnancy.

The study was led by researchers from the Van Andel Institute and Pine Rest Christian Mental Health Services and published in Translational Psychiatry.

The team’s analysis identified a set of 15 biological markers found in the blood that can predict with an 83 percent accuracy whether pregnant women will experience significant depressive symptoms. The findings could give physicians a much-needed tool to identify women at risk for depression and better tailor their care during pregnancy.

Almost one in five new moms will experience major depression during or after pregnancy, and an estimated 14 percent have suicidal thoughts. Inflammation can lead to worsening of depressive symptoms, and pregnancy is a major inflammatory event.

“Depression isn’t just something that happens in the brain — its fingerprints are everywhere in the body, including our blood,” said Lena Brundin, MD, PhD, a VAI professor and co-author of the study. “The ability to predict pregnancy-related depression and its severity will be a critical factor in protecting the health of mothers and their infants. Our results are an important step towards this goal.”

This study, among the first of its kind, followed 114 volunteers from Spectrum Health’s obstetrics and gynecology clinics throughout their pregnancy. Participants provided blood samples and were clinically evaluated for depressive symptoms each trimester and postpartum period.

“An objective and easily accessible method related to the risk of depression, such as A blood test, for example, provides a unique tool for identifying women at risk of depression during pregnancy,” said Eric Achtyes, MD, MS, associate psychiatrist at Pine Rest, an associate professor at Michigan State University and co-senior -Author of the study.

“Our results are an exciting development and an important first step towards more broadly using these types of methods to help patients. Our next steps include replicating the results in additional patient samples to check the breakpoints for depression risk,” concluded Achtyes.

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This story was published from a wire agency feed with no changes to the text. Only the headline has been changed.



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