Getting to know nocebo, thought-triggered side effects of the Covid vaccine – Archyde

Jakarta, CNN Indonesia

Recent studies show the majority of side effects vaccination Covid-19 arises because it is triggered by thoughts or suggestions. This side effect is called a nocebo.

What is a nocebo?

Quoted from Merriam-Webster, Nocebo is a side effect or worsening symptom of a harmless treatment due to expectations or the patient’s mental state. Generally, these side effects occur because of perceptions, suggestions, or beliefs that a person believes.

Nocebo is different from the placebo effect. Placebo drugs are drugs that are given to the patient but have no effect on the patient.

What are the side effects of Nocebo in recipients of Covid-19 vaccines?

A study recently published in the journal JAMA Network Open showed that nearly two-thirds of the Covid-19 vaccine’s side effects, such as headaches and fatigue, were due to the nocebo.

The results came after researchers analyzed data from 12 clinical trials of a Covid-19 vaccine in 22,802 people, compared with 22,578 people who received a placebo injection. The placebo injection is an empty injection that contains no vaccine and has no effect on the patient. Placebo recipients were not told they were receiving a placebo.

As a result, more than 35 percent of placebo recipients experienced symptoms affecting the whole body, such as fever, headache and fatigue. Up to 16 percent of placebo recipients also had a local symptom, such as pain at the injection site, redness, or swelling.

Meanwhile, in the group that received the vaccine, 46 percent had at least one systemic side effect and two-thirds reported a local symptom.

The researchers then concluded that the side effects experienced by the vaccine recipients were nocebo effects, since many of the same effects were also seen in the placebo group.

“Non-specific symptoms such as headache and fatigue – which we have shown to be very sensitive to nocebo – were among the most common post-Covid-19 vaccination adverse reactions reported in many information leaflets,” researcher Ted J. Kaptchuk said in a statement. Independent.

Another finding: after the second dose of vaccine, side effects were less in both the vaccine and placebo recipients. According to the researchers, this happened because the vaccine recipients pre-empted themselves so that they would not experience side effects like the first injection dose.

In order to prevent nocebo side effects during vaccination, vaccinates are advised to eliminate fear and believe that vaccination will actually have a positive effect on the body.


[Gambas:Video CNN]

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